It was obvious pretty early on when setting up my configuration that spellcasting was not going to be my biggest problem; movement was. Because while using abilities and casting spells, opening and closing interface panels, and even targeting other players are very binary actions, it is infeasible to play without the analog mouselook feature (I tried). I have had good luck using a SmartNav: EG head tracker at work, an assistive device I had purchased out-of-pocket to reduce my use of the mouse as a software developer. This camera tracks the movement of a small, reflective silver dot that you wear somewhere on the top of your head. That movement is then translated into mouse movement on-screen. Once I was certain of its efficacy, I requested that my work buy one for my use at the office so that I could take the one I had purchased home.
To hopefully pique your interest, I have created a short video of me demonstrating all of the techniques in this post: